Parasitic Germplasm Resource and Control of Parasitosis for Domestic Animal and Poultry in Sichuan and South-western China / 中国寄生虫学与寄生虫病杂志

The object of using parasitic germplasm resource is to raise the technical level to control parsitosis for domestic animal and poultry.A total of 1 036 parasitic species collected from 16 kinds of domestic animals and poultries were reported in South-western China,where is one of the most serious areas for parasitosis transmission in China.This paper described the research and use of the new techniques on diagnosis,surveillance and control of parasitosis in domestic animal and poultry in Sichuan and South-western China,especially on applying resources of parasitic species in the pilot areas,so that the capacity of control and prevent of parasitosis in sheep,pig and dairy cattle farms were reasonably improved.

The effect of entrapment of CpG sequence with cationic PLG nanoparticles on the immune responses of mice to pig paratyphoid vaccine / 生物医学工程学杂志

Cationic PLG nanoparticles and liposome were prepared and used as package molecules to pack up pUC18-CpG. The effects of the packed pUC18-CpG on the cellular and humoral immune responses were detected in the mice that were inoculated with pig paratyphoid vaccine. The results showed that compared with the control, the amount of IgG and the titre of specific antibody were significantly increased in the sera of mice immunized with the CpG plasmid entrapped by cationic PLG nanoparticles; the proliferation and induced IL-2 bioactivity of lymphocytes were significantly enhanced in the spleen of the immunized mice; the stimulatory effect of cationic PLG nanoparticles was similar to or stronger than that of cationic liposome. These indicated that cationic PLG nanoparticle could be employed as an effective package molecule to promote the immunostimulatory effect of pUC18-CpG.

Application of Estrogen Receptor Binding Assay in the Endocrine Disrupting Chemicals Screening Tests / 环境与健康杂志

Estrogen receptor binding assay is to assess the estrogenic activity of chemicals by determining the ability of competing with 17?-estradiol to bind with estrogen receptor.It has the strengths of simplicity,speediness with good reproducibility.This literature reviewed mainly the mechanism,the research progress,test method,influencing factors of this assay as well as its application.